Cheapest one-way flights from Madrid to Panama City in November from 290€

AirHint found the following cheapest one-way flights from Madrid (MAD) to Panama City (PTY) in November 2025 (see full year).

One-Way flights

24 Nov Air Europa direct
21 Nov Air Europa direct
07 Nov Air Europa direct
06 Nov Air Europa direct
23 Nov Air Europa direct
17 Nov Air Europa direct
14 Nov Air Europa direct
15 Nov Air Europa direct
22 Nov Iberia direct
16 Nov Air Europa direct

Also check the deals for return flights from Madrid to Panama City in November.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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