AirHint found the following cheapest return flights from Quito (UIO) to Santiago (SCL) in August 2025 (see full year).

Return flights

29 Aug - 05 Sep	JetSmart
29 Aug - 03 Sep	JetSmart
31 Aug - 05 Sep	JetSmart
31 Aug - 03 Sep	JetSmart
27 Aug - 05 Sep	JetSmart
24 Aug - 05 Sep	JetSmart
29 Aug - 10 Sep	JetSmart
20 Aug - 05 Sep	JetSmart
24 Aug - 03 Sep	JetSmart
26 Aug - 05 Sep	Avianca
27 Aug - 29 Aug	JetSmart
24 Aug - 29 Aug	JetSmart
22 Aug - 29 Aug	Avianca
20 Aug - 29 Aug	JetSmart
18 Aug - 29 Aug	JetSmart
18 Aug - 20 Aug	JetSmart
19 Aug - 26 Aug	Avianca
20 Aug - 23 Aug	JetSmart
16 Aug - 19 Aug	LATAM Airlines Group
18 Aug - 23 Aug	JetSmart

Also check the deals for one-way flights from Quito to Santiago in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Santiago in August from 282€

Return flights