AirHint found the following cheapest return flights from Quito (UIO) to Santiago (SCL) in January 2026 (see full year).

Return flights

15 Jan - 18 Jan	JetSmart
15 Jan - 03 Feb	JetSmart
11 Jan - 18 Jan	JetSmart
04 Jan - 18 Jan	JetSmart
14 Jan - 18 Jan	JetSmart
07 Jan - 18 Jan	JetSmart
15 Jan - 17 Feb	JetSmart
04 Jan - 06 Jan	JetSmart
18 Jan - 03 Feb	JetSmart
04 Jan - 11 Jan	JetSmart
14 Jan - 03 Feb	JetSmart
30 Jan - 17 Feb	JetSmart
07 Jan - 11 Jan	JetSmart
30 Jan - 12 Feb	JetSmart
30 Jan - 03 Feb	JetSmart
01 Jan - 15 Jan	Avianca
06 Jan - 10 Jan	Copa

Also check the deals for one-way flights from Quito to Santiago in January.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Santiago in January from 304€

Return flights