AirHint found the following cheapest return flights from Quito (UIO) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

17 Oct - 21 Oct	LATAM Airlines Group
06 Oct - 10 Oct	LATAM Airlines Group
01 Oct - 06 Oct	LATAM Airlines Group
18 Oct - 22 Oct	Copa
20 Oct - 30 Oct	Copa
22 Oct - 28 Oct	Copa
28 Oct - 01 Nov	Copa
15 Oct - 22 Oct	Avianca
15 Oct - 21 Oct	LATAM Airlines Group
03 Oct - 06 Oct	LATAM Airlines Group
05 Oct - 08 Oct	LATAM Airlines Group
28 Oct - 02 Nov	Copa
31 Oct - 04 Nov	Copa

Also check the deals for one-way flights from Quito to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Rio Negro in October from 222€

Return flights