AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in April 2026 (see full year).

Return flights

28 Apr - 12 May	Air Europa	direct
23 Apr - 09 May	Air Europa	direct
20 Apr - 04 May	Avianca
22 Apr - 02 May	Avianca
29 Apr - 03 May	Avianca
18 Apr - 08 May	Avianca
08 Apr - 22 Apr	Avianca
08 Apr - 17 Apr	Iberia	direct
01 Apr - 08 Apr	Avianca
08 Apr - 29 Apr	Avianca
01 Apr - 08 Apr	Iberia	direct
08 Apr - 22 Apr	LATAM Airlines Group	direct
03 Apr - 19 Apr	LATAM Airlines Group
20 Apr - 04 May	Iberia	direct
30 Apr - 03 May	Avianca
29 Apr - 03 May	LATAM Airlines Group	direct
30 Apr - 24 May	Avianca

Also check the deals for one-way flights from Quito to Madrid in April.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in April from 731€

Return flights