AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in November 2025 (see full year).

Return flights

17 Nov - 24 Nov	Iberia
11 Nov - 25 Nov	Iberia
14 Nov - 23 Nov	Iberia
04 Nov - 27 Nov	Iberia
06 Nov - 24 Nov	Iberia
06 Nov - 27 Nov	Iberia
04 Nov - 24 Nov	Iberia
06 Nov - 18 Nov	Iberia
18 Nov - 25 Nov	Iberia
20 Nov - 27 Nov	Iberia
28 Nov - 26 Dec	Avianca
07 Nov - 09 Dec	Avianca
19 Nov - 06 Dec	Avianca
07 Nov - 09 Dec	Iberia	direct
21 Nov - 07 Dec	Iberia
22 Nov - 06 Dec	Air Europa	direct
28 Nov - 26 Dec	LATAM Airlines Group	direct

Also check the deals for one-way flights from Quito to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in November from 642€

Return flights