AirHint found the following cheapest return flights from Quito (UIO) to Madrid (MAD) in October 2025 (see full year).

Return flights

23 Oct - 13 Nov	Air Europa	direct
30 Oct - 13 Nov	Air Europa	direct
13 Oct - 07 Nov	LATAM Airlines Group
16 Oct - 18 Oct	Air Europa	direct
24 Oct - 03 Nov	Avianca
13 Oct - 15 Oct	Avianca
09 Oct - 23 Oct	Air Europa	direct
03 Oct - 14 Oct	Avianca
17 Oct - 24 Oct	Avianca
05 Oct - 21 Oct	Avianca
24 Oct - 31 Oct	Avianca
09 Oct - 21 Oct	Air Europa	direct
29 Oct - 23 Nov	Iberia	direct
23 Oct - 06 Nov	Iberia
29 Oct - 09 Nov	Avianca
28 Oct - 02 Nov	Avianca
06 Oct - 19 Oct	Avianca
20 Oct - 31 Oct	Avianca
24 Oct - 28 Nov	Iberia
24 Oct - 09 Nov	Avianca

Also check the deals for one-way flights from Quito to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Quito to Madrid in October from 660€

Return flights