AirHint found the following cheapest return flights from Trujillo (TRU) to Santiago (SCL) in September 2025 (see full year).

Return flights

24 Sep - 01 Oct	LATAM Airlines Group
29 Sep - 13 Oct	JetSmart	direct
27 Sep - 13 Oct	JetSmart	direct
27 Sep - 04 Oct	LATAM Airlines Group
29 Sep - 10 Oct	JetSmart	direct
29 Sep - 06 Oct	JetSmart	direct
29 Sep - 04 Oct	JetSmart	direct
27 Sep - 10 Oct	JetSmart	direct
27 Sep - 06 Oct	JetSmart	direct
27 Sep - 04 Oct	JetSmart	direct
27 Sep - 29 Sep	JetSmart	direct

Also check the deals for one-way flights from Trujillo to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Trujillo to Santiago in September from 290€

Return flights