AirHint found the following cheapest return flights from Tenerife (TFS) to Prague (PRG) in October 2025 (see full year).

Return flights

02 Oct - 09 Oct	Ryanair
09 Oct - 15 Oct	easyJet
29 Oct - 01 Nov	SWISS
10 Oct - 15 Oct	Ryanair
05 Oct - 05 Nov	Lufthansa
04 Oct - 11 Oct	Ryanair
02 Oct - 05 Oct	Ryanair
15 Oct - 18 Oct	easyJet
16 Oct - 16 Oct	Ryanair
28 Oct - 31 Oct	Ryanair
03 Oct - 05 Oct	easyJet
14 Oct - 19 Oct	Ryanair
29 Oct - 01 Nov	Smart Wings	direct

Also check the deals for one-way flights from Tenerife to Prague in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Tenerife to Prague in October from 159€

Return flights