AirHint found the following cheapest return flights from Split (SPU) to Prague (PRG) in September 2025 (see full year).

Return flights

23 Sep - 26 Sep	Vueling Airlines
04 Sep - 06 Sep	Austrian Airlines
24 Sep - 28 Sep	Lufthansa
18 Sep - 21 Sep	Lufthansa
08 Sep - 13 Sep	Smart Wings
24 Sep - 28 Sep	Smart Wings	direct
12 Sep - 16 Sep	SWISS
08 Sep - 13 Sep	Croatia Airlines	direct
04 Sep - 06 Sep	Smart Wings	direct
18 Sep - 21 Sep	Smart Wings	direct

Also check the deals for one-way flights from Split to Prague in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Split to Prague in September from 133€

Return flights