AirHint found the following cheapest return flights from San Jose (SJO) to Santiago (SCL) in September 2025 (see full year).

Return flights

30 Sep - 23 Oct	Avianca
30 Sep - 21 Oct	Avianca
30 Sep - 16 Oct	Avianca
15 Sep - 20 Sep	Avianca
09 Sep - 24 Sep	Avianca
17 Sep - 24 Sep	Avianca
15 Sep - 22 Sep	Avianca
09 Sep - 09 Oct	Avianca
30 Sep - 07 Oct	Avianca
24 Sep - 30 Sep	Copa
12 Sep - 18 Sep	Avianca
12 Sep - 20 Sep	Avianca
29 Sep - 13 Oct	Avianca
30 Sep - 20 Oct	Avianca
18 Sep - 25 Sep	Avianca
23 Sep - 29 Sep	Copa
23 Sep - 30 Sep	Copa

Also check the deals for one-way flights from San Jose to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Jose to Santiago in September from 321€

Return flights