AirHint found the following cheapest return flights from San Jose (SJO) to Santiago (SCL) in September 2025 (see full year).

Return flights

15 Sep - 23 Sep	LATAM Airlines Group
16 Sep - 23 Sep	LATAM Airlines Group
23 Sep - 30 Sep	Copa
16 Sep - 21 Sep	Avianca
09 Sep - 01 Oct	Avianca
10 Sep - 01 Oct	Avianca
12 Sep - 16 Sep	Avianca
29 Sep - 06 Oct	Avianca
25 Sep - 05 Oct	Avianca
25 Sep - 04 Oct	Avianca
01 Sep - 06 Sep	Avianca
12 Sep - 21 Sep	Avianca
12 Sep - 20 Sep	Avianca
14 Sep - 21 Sep	Avianca
16 Sep - 07 Oct	Avianca
15 Sep - 27 Sep	Copa
09 Sep - 09 Oct	Copa
27 Sep - 04 Oct	Avianca

Also check the deals for one-way flights from San Jose to Santiago in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Jose to Santiago in September from 310€

Return flights