AirHint found the following cheapest return flights from San Francisco (SFO) to Panama City (PTY) in November 2025 (see full year).

Return flights

01 Nov - 03 Nov	Avianca
27 Nov - 02 Dec	Copa	direct
01 Nov - 03 Nov	Copa	direct
08 Nov - 15 Nov	Copa	direct
03 Nov - 10 Nov	United	direct
21 Nov - 30 Nov	Porter Airlines (Canada) Ltd
23 Nov - 29 Nov	United	direct
21 Nov - 30 Nov	Copa	direct

Also check the deals for one-way flights from San Francisco to Panama City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Panama City in November from 434€

Return flights