AirHint found the following cheapest return flights from San Francisco (SFO) to Madrid (MAD) in September 2025 (see full year).

Return flights

27 Sep - 07 Oct	Delta
24 Sep - 07 Oct	Air France
16 Sep - 23 Sep	Lufthansa
16 Sep - 16 Oct	SWISS
17 Sep - 24 Sep	British Airways	direct
25 Sep - 07 Oct	Air France
16 Sep - 07 Oct	Delta
16 Sep - 26 Sep	Delta
25 Sep - 14 Oct	Delta
27 Sep - 04 Oct	Virgin Atlantic
15 Sep - 22 Sep	Air France
23 Sep - 01 Oct	British Airways
24 Sep - 01 Oct	British Airways
22 Sep - 29 Sep	Lufthansa
16 Sep - 28 Oct	SWISS
23 Sep - 29 Sep	SWISS
15 Sep - 25 Sep	United
16 Sep - 23 Sep	Finnair	direct
14 Sep - 20 Sep	Brussels Airlines
16 Sep - 30 Sep	Lufthansa

Also check the deals for one-way flights from San Francisco to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from San Francisco to Madrid in September from 367€

Return flights