AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

31 Dec - 14 Jan	KLM
31 Dec - 19 Jan	Air France
06 Dec - 27 Dec	Air France
31 Dec - 14 Jan	Turkish Airlines	direct
25 Dec - 08 Jan	KLM
29 Dec - 31 Jan	Delta
02 Dec - 31 Dec	FrenchBee
17 Dec - 31 Dec	KLM
22 Dec - 05 Jan	British Airways
22 Dec - 30 Dec	British Airways
31 Dec - 19 Jan	Turkish Airlines	direct
25 Dec - 08 Jan	Turkish Airlines	direct
24 Dec - 31 Dec	Turkish Airlines	direct
22 Dec - 30 Dec	Turkish Airlines	direct
22 Dec - 05 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Istanbul in December from 633€

Return flights