AirHint found the following cheapest return flights from San Francisco (SFO) to Istanbul (IST) in December 2025 (see full year).

Return flights

01 Dec - 08 Dec	SWISS
10 Dec - 24 Dec	Lufthansa
07 Dec - 27 Dec	KLM
07 Dec - 21 Dec	SWISS
15 Dec - 18 Dec	KLM
03 Dec - 24 Dec	KLM
25 Dec - 16 Jan	Air France
16 Dec - 20 Jan	KLM
25 Dec - 17 Jan	Air France
12 Dec - 26 Dec	KLM
24 Dec - 07 Jan	Hawaiian Airlines
24 Dec - 31 Dec	British Airways
24 Dec - 05 Jan	British Airways
25 Dec - 10 Jan	Scandinavian Airlines
02 Dec - 23 Dec	KLM
10 Dec - 24 Dec	Turkish Airlines	direct
08 Dec - 03 Jan	Hawaiian Airlines
25 Dec - 16 Jan	Turkish Airlines	direct
25 Dec - 17 Jan	Turkish Airlines	direct
25 Dec - 10 Jan	Turkish Airlines	direct

Also check the deals for one-way flights from San Francisco to Istanbul in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Francisco to Istanbul in December from 570€

Return flights