AirHint found the following cheapest return flights from Santander (SDR) to Istanbul (IST) in December 2025 (see full year).
Return flights
| 15 Dec - 01 Jan | Ryanair | ||
| 21 Dec - 28 Dec | Volotea | ||
| 24 Dec - 05 Jan | Iberia | ||
| 22 Dec - 29 Dec | Volotea | ||
| 26 Dec - 02 Jan | Ryanair | ||
| 22 Dec - 26 Dec | Iberia |
Also check the deals for one-way flights from Santander to Istanbul in December.
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