AirHint found the following cheapest return flights from Santiago (SCL) to Panama City (PTY) in August 2025 (see full year).

Return flights

06 Aug - 10 Aug	Avianca
04 Aug - 14 Aug	Avianca
14 Aug - 17 Aug	Avianca
09 Aug - 23 Aug	JetSmart
14 Aug - 21 Aug	Avianca
11 Aug - 20 Aug	Avianca
08 Aug - 15 Aug	Avianca
28 Aug - 07 Sep	Avianca
04 Aug - 09 Aug	Avianca
11 Aug - 20 Aug	Copa	direct
08 Aug - 15 Aug	Copa	direct
14 Aug - 21 Sep	Avianca
15 Aug - 21 Sep	Avianca
14 Aug - 21 Sep	Copa	direct
15 Aug - 21 Sep	Copa	direct

Also check the deals for one-way flights from Santiago to Panama City in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Panama City in August from 489€

Return flights