AirHint found the following cheapest return flights from Santiago (SCL) to Mexico City (MEX) in September 2025 (see full year).

Return flights

03 Sep - 11 Sep	Arajet
29 Sep - 14 Oct	Arajet
24 Sep - 14 Oct	Arajet
03 Sep - 09 Sep	Arajet
01 Sep - 14 Sep	Avianca
05 Sep - 14 Sep	Avianca
04 Sep - 11 Sep	Avianca
30 Sep - 14 Oct	Avianca
12 Sep - 12 Oct	Arajet
17 Sep - 24 Sep	LATAM Airlines Group
26 Sep - 30 Sep	Avianca
22 Sep - 06 Oct	Avianca
04 Sep - 06 Sep	Avianca
26 Sep - 02 Oct	Avianca
11 Sep - 24 Sep	LATAM Airlines Group
10 Sep - 27 Sep	Avianca
10 Sep - 10 Oct	Avianca
26 Sep - 02 Oct	LATAM Airlines Group	direct

Also check the deals for one-way flights from Santiago to Mexico City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Mexico City in September from 396€

Return flights