AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

07 Sep - 27 Sep	JetSmart
22 Sep - 27 Sep	JetSmart
22 Sep - 12 Oct	JetSmart
24 Sep - 27 Sep	JetSmart
24 Sep - 12 Oct	JetSmart
07 Sep - 16 Sep	JetSmart
07 Sep - 13 Sep	JetSmart
17 Sep - 27 Sep	JetSmart
21 Sep - 27 Sep	JetSmart
22 Sep - 30 Sep	JetSmart
03 Sep - 16 Sep	JetSmart
03 Sep - 13 Sep	JetSmart
24 Sep - 01 Oct	JetSmart
03 Sep - 17 Oct	JetSmart
28 Sep - 12 Oct	JetSmart
22 Sep - 09 Oct	JetSmart
22 Sep - 01 Oct	JetSmart
22 Sep - 10 Oct	JetSmart
24 Sep - 09 Oct	JetSmart
24 Sep - 10 Oct	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in September from 283€

Return flights