AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

03 Sep - 09 Sep	JetSmart
27 Sep - 29 Sep	JetSmart
19 Sep - 29 Sep	JetSmart
17 Sep - 29 Sep	JetSmart
22 Sep - 29 Sep	JetSmart
27 Sep - 05 Oct	JetSmart
24 Sep - 29 Sep	JetSmart
05 Sep - 13 Sep	Copa
20 Sep - 26 Sep	Copa
25 Sep - 29 Sep	Avianca
18 Sep - 29 Sep	JetSmart
19 Sep - 05 Oct	JetSmart
17 Sep - 05 Oct	JetSmart
19 Sep - 06 Oct	JetSmart
27 Sep - 03 Oct	JetSmart
17 Sep - 06 Oct	JetSmart
19 Sep - 03 Oct	JetSmart
22 Sep - 05 Oct	JetSmart
17 Sep - 03 Oct	JetSmart
22 Sep - 06 Oct	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in September from 272€

Return flights