AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

01 Dec - 03 Dec	JetSmart	direct
07 Dec - 14 Dec	JetSmart	direct
01 Dec - 14 Dec	JetSmart	direct
07 Dec - 24 Dec	JetSmart
08 Dec - 24 Dec	JetSmart
07 Dec - 30 Jan	JetSmart	direct
01 Dec - 05 Dec	JetSmart	direct
07 Dec - 17 Dec	JetSmart	direct
01 Dec - 17 Dec	JetSmart	direct
10 Dec - 14 Dec	JetSmart	direct
10 Dec - 24 Dec	JetSmart
26 Dec - 07 Jan	JetSmart	direct
24 Dec - 07 Jan	JetSmart	direct
21 Dec - 07 Jan	JetSmart
27 Dec - 07 Jan	JetSmart
20 Dec - 07 Jan	JetSmart
24 Dec - 11 Jan	JetSmart	direct
26 Dec - 11 Jan	JetSmart	direct
21 Dec - 11 Jan	JetSmart
26 Dec - 12 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in December from 253€

Return flights