AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in December 2025 (see full year).

Return flights

15 Dec - 29 Dec	JetSmart	direct
29 Dec - 11 Jan	JetSmart	direct
08 Dec - 10 Dec	JetSmart	direct
15 Dec - 17 Dec	JetSmart	direct
01 Dec - 08 Dec	JetSmart	direct
21 Dec - 27 Jan	JetSmart
10 Dec - 14 Dec	JetSmart	direct
01 Dec - 07 Dec	JetSmart	direct
14 Dec - 17 Dec	JetSmart	direct
14 Dec - 15 Dec	JetSmart	direct
05 Dec - 14 Dec	JetSmart	direct
05 Dec - 07 Dec	JetSmart	direct
15 Dec - 30 Jan	JetSmart	direct
15 Dec - 02 Jan	JetSmart
15 Dec - 02 Jan	JetSmart	direct
14 Dec - 02 Jan	JetSmart
14 Dec - 02 Jan	JetSmart	direct
15 Dec - 03 Jan	JetSmart
18 Dec - 05 Jan	JetSmart
13 Dec - 28 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in December from 213€

Return flights