AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

14 Oct - 28 Oct	LATAM Airlines Group
24 Oct - 02 Nov	JetSmart
18 Oct - 02 Nov	JetSmart
25 Oct - 02 Nov	JetSmart
14 Oct - 20 Oct	LATAM Airlines Group
15 Oct - 02 Nov	JetSmart
22 Oct - 02 Nov	JetSmart
19 Oct - 02 Nov	JetSmart
10 Oct - 14 Oct	LATAM Airlines Group
20 Oct - 02 Nov	JetSmart
24 Oct - 28 Oct	JetSmart
22 Oct - 26 Oct	LATAM Airlines Group
06 Oct - 20 Oct	LATAM Airlines Group
08 Oct - 15 Oct	LATAM Airlines Group
18 Oct - 28 Oct	JetSmart
24 Oct - 25 Oct	JetSmart
15 Oct - 28 Oct	JetSmart
14 Oct - 02 Nov	JetSmart
30 Oct - 03 Nov	Avianca
27 Oct - 14 Nov	Avianca

Also check the deals for one-way flights from Santiago to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in October from 293€

Return flights