AirHint found the following cheapest return flights from Santiago (SCL) to Rio Negro (MDE) in October 2025 (see full year).

Return flights

03 Oct - 05 Oct	JetSmart
20 Oct - 27 Oct	JetSmart
20 Oct - 10 Nov	JetSmart
20 Oct - 21 Oct	JetSmart
03 Oct - 06 Oct	JetSmart
20 Oct - 22 Oct	JetSmart
19 Oct - 27 Oct	JetSmart
03 Oct - 21 Oct	JetSmart
19 Oct - 21 Oct	JetSmart
03 Oct - 22 Oct	JetSmart
19 Oct - 22 Oct	JetSmart
22 Oct - 10 Nov	JetSmart
24 Oct - 07 Nov	Avianca
24 Oct - 10 Nov	JetSmart
22 Oct - 11 Nov	JetSmart
29 Oct - 02 Nov	Avianca
20 Oct - 07 Nov	JetSmart
23 Oct - 10 Nov	JetSmart
19 Oct - 07 Nov	JetSmart
24 Oct - 11 Nov	JetSmart

Also check the deals for one-way flights from Santiago to Rio Negro in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rio Negro in October from 282€

Return flights