AirHint found the following cheapest return flights from Santiago (SCL) to Guayaquil (GYE) in August 2025 (see full year).

Return flights

18 Aug - 25 Aug	Avianca
21 Aug - 07 Sep	Avianca
28 Aug - 03 Sep	Copa
19 Aug - 24 Aug	Avianca
22 Aug - 31 Aug	Avianca
30 Aug - 03 Sep	Copa
18 Aug - 31 Aug	Copa
18 Aug - 25 Aug	LATAM Airlines Group	direct

Also check the deals for one-way flights from Santiago to Guayaquil in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Guayaquil in August from 341€

Return flights