AirHint found the following cheapest return flights from Santiago (SCL) to Rome (FCO) in December 2025 (see full year).

Return flights

24 Dec - 13 Jan	Air Canada
30 Dec - 22 Jan	Iberia
21 Dec - 22 Jan	Iberia
31 Dec - 22 Jan	Iberia
23 Dec - 06 Jan	KLM
20 Dec - 17 Jan	Sky Airline
22 Dec - 10 Jan	Avianca
21 Dec - 28 Dec	Iberia
22 Dec - 11 Jan	LATAM Airlines Group
25 Dec - 01 Jan	Air France
29 Dec - 08 Jan	Copa
22 Dec - 29 Dec	KLM

Also check the deals for one-way flights from Santiago to Rome in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Rome in December from 924€

Return flights