AirHint found the following cheapest return flights from Santiago (SCL) to Cali (CLO) in December 2025 (see full year).

Return flights

02 Dec - 07 Dec	JetSmart
06 Dec - 07 Dec	JetSmart
09 Dec - 26 Dec	JetSmart
01 Dec - 07 Dec	JetSmart
01 Dec - 16 Dec	Avianca
05 Dec - 07 Dec	JetSmart
04 Dec - 07 Dec	JetSmart
02 Dec - 06 Dec	JetSmart
06 Dec - 26 Dec	JetSmart
09 Dec - 16 Dec	JetSmart
07 Dec - 08 Jan	LATAM Airlines Group
09 Dec - 31 Jan	JetSmart
03 Dec - 07 Jan	JetSmart
31 Dec - 21 Jan	JetSmart	direct
06 Dec - 08 Jan	LATAM Airlines Group
03 Dec - 06 Jan	JetSmart
02 Dec - 07 Jan	JetSmart
09 Dec - 02 Jan	JetSmart
10 Dec - 07 Jan	LATAM Airlines Group
11 Dec - 17 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Cali in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Cali in December from 358€

Return flights