AirHint found the following cheapest return flights from Santiago (SCL) to Cali (CLO) in December 2025 (see full year).

Return flights

31 Dec - 15 Jan	LATAM Airlines Group
30 Dec - 31 Dec	Copa
30 Dec - 26 Jan	LATAM Airlines Group
31 Dec - 11 Jan	LATAM Airlines Group
31 Dec - 08 Jan	LATAM Airlines Group
30 Dec - 22 Jan	Avianca
30 Dec - 08 Jan	Avianca
28 Dec - 23 Jan	Avianca
30 Dec - 12 Jan	Avianca
30 Dec - 15 Jan	Avianca
29 Dec - 30 Dec	JetSmart
25 Dec - 26 Dec	JetSmart	direct
25 Dec - 30 Dec	JetSmart	direct
31 Dec - 21 Jan	JetSmart
29 Dec - 31 Dec	JetSmart
25 Dec - 31 Dec	JetSmart	direct
28 Dec - 30 Dec	JetSmart
27 Dec - 30 Dec	JetSmart
30 Dec - 30 Dec	JetSmart
29 Dec - 30 Dec	JetSmart	direct

Also check the deals for one-way flights from Santiago to Cali in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Cali in December from 360€

Return flights