AirHint found the following cheapest return flights from Santiago (SCL) to Cali (CLO) in December 2025 (see full year).

Return flights

03 Dec - 18 Dec	JetSmart
10 Dec - 18 Dec	JetSmart
11 Dec - 18 Dec	JetSmart
09 Dec - 18 Dec	JetSmart
04 Dec - 18 Dec	Avianca
10 Dec - 16 Jan	Copa
03 Dec - 07 Jan	JetSmart	direct
03 Dec - 04 Dec	JetSmart
03 Dec - 11 Dec	JetSmart
10 Dec - 11 Dec	JetSmart
03 Dec - 05 Dec	JetSmart
11 Dec - 11 Jan	JetSmart	direct
03 Dec - 18 Dec	JetSmart	direct
31 Dec - 11 Jan	JetSmart	direct
30 Dec - 11 Jan	JetSmart
11 Dec - 20 Jan	JetSmart
31 Dec - 05 Jan	JetSmart	direct
31 Dec - 20 Jan	JetSmart
30 Dec - 05 Jan	JetSmart
22 Dec - 11 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Cali in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Cali in December from 249€

Return flights