AirHint found the following cheapest return flights from Santiago (SCL) to Asuncion (ASU) in December 2025 (see full year).

Return flights

14 Dec - 21 Dec	JetSmart
14 Dec - 28 Dec	JetSmart
14 Dec - 26 Dec	JetSmart
14 Dec - 30 Dec	JetSmart
14 Dec - 02 Jan	JetSmart
18 Dec - 21 Dec	JetSmart
18 Dec - 28 Dec	JetSmart
18 Dec - 26 Dec	JetSmart
18 Dec - 30 Dec	JetSmart
21 Dec - 28 Dec	JetSmart
21 Dec - 26 Dec	JetSmart
18 Dec - 02 Jan	JetSmart
21 Dec - 02 Jan	JetSmart
21 Dec - 11 Jan	JetSmart

Also check the deals for one-way flights from Santiago to Asuncion in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Santiago to Asuncion in December from 228€

Return flights