AirHint found the following cheapest return flights from San Pedro Sula (SAP) to Panama City (PTY) in September 2025 (see full year).

Return flights

09 Sep - 11 Sep	Copa	direct
09 Sep - 12 Sep	Copa	direct
13 Sep - 15 Sep	Copa	direct
06 Sep - 07 Sep	Copa	direct
12 Sep - 14 Sep	Avianca
01 Sep - 08 Sep	Avianca
02 Sep - 05 Sep	Avianca
02 Sep - 05 Sep	Copa	direct
01 Sep - 08 Sep	Copa	direct
27 Sep - 02 Oct	Avianca
12 Sep - 14 Sep	Copa	direct
24 Sep - 03 Oct	Copa	direct
30 Sep - 05 Oct	Avianca
11 Sep - 05 Oct	Avianca
28 Sep - 05 Oct	Avianca
11 Sep - 05 Oct	Copa	direct
29 Sep - 04 Oct	Copa	direct
30 Sep - 05 Oct	Copa	direct
28 Sep - 05 Oct	Copa	direct

Also check the deals for one-way flights from San Pedro Sula to Panama City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Pedro Sula to Panama City in September from 301€

Return flights