AirHint found the following cheapest return flights from San Pedro Sula (SAP) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 02 Dec - 06 Dec | Copa | direct | |
| 11 Dec - 18 Dec | Copa | direct | |
| 01 Dec - 06 Dec | Copa | direct | |
| 22 Dec - 27 Dec | Copa | direct | |
| 18 Dec - 05 Jan | Copa | direct | |
| 19 Dec - 20 Jan | Copa | direct | |
| 10 Dec - 17 Dec | Spirit Airlines |
Also check the deals for one-way flights from San Pedro Sula to Panama City in December.
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