AirHint found the following cheapest return flights from San Diego (SAN) to Madrid (MAD) in September 2025 (see full year).

Return flights

23 Sep - 30 Sep	United
22 Sep - 30 Sep	Air Canada
23 Sep - 14 Oct	Air Canada
22 Sep - 03 Oct	Air Canada
08 Sep - 19 Sep	United
08 Sep - 26 Sep	Air Canada
16 Sep - 23 Sep	Air Canada
30 Sep - 29 Oct	KLM
08 Sep - 25 Sep	Air France
01 Sep - 18 Sep	Air Canada
23 Sep - 01 Oct	British Airways
29 Sep - 09 Oct	Air France
02 Sep - 09 Sep	United
23 Sep - 20 Oct	Delta
29 Sep - 06 Oct	United
08 Sep - 27 Sep	Air Canada
08 Sep - 28 Sep	Air Canada
10 Sep - 10 Oct	Delta
20 Sep - 05 Oct	Delta
17 Sep - 03 Oct	Delta

Also check the deals for one-way flights from San Diego to Madrid in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Diego to Madrid in September from 407€

Return flights