AirHint found the following cheapest return flights from San Diego (SAN) to Madrid (MAD) in October 2025 (see full year).

Return flights

05 Oct - 14 Oct	United
14 Oct - 21 Oct	United
06 Oct - 17 Oct	United
08 Oct - 23 Oct	Air France
01 Oct - 16 Oct	Delta
03 Oct - 16 Oct	Air France
24 Oct - 07 Nov	Air France
24 Oct - 31 Oct	Iberia
09 Oct - 16 Oct	Iberia
24 Oct - 26 Oct	Delta
02 Oct - 25 Oct	Delta
26 Oct - 01 Nov	Lufthansa

Also check the deals for one-way flights from San Diego to Madrid in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from San Diego to Madrid in October from 487€

Return flights