AirHint found the following cheapest return flights from San Diego (SAN) to Rome (FCO) in December 2025 (see full year).

Return flights

30 Dec - 18 Jan	Lufthansa
02 Dec - 23 Dec	Lufthansa
06 Dec - 10 Jan	Air Canada
02 Dec - 06 Dec	Alaska Airlines
29 Dec - 12 Jan	British Airways
23 Dec - 09 Jan	Hawaiian Airlines
23 Dec - 17 Jan	Lufthansa
15 Dec - 05 Jan	British Airways
06 Dec - 27 Dec	Alaska Airlines
24 Dec - 31 Dec	Lufthansa
27 Dec - 05 Jan	British Airways
09 Dec - 03 Jan	Hawaiian Airlines
23 Dec - 05 Jan	Hawaiian Airlines
12 Dec - 03 Jan	Hawaiian Airlines
11 Dec - 18 Dec	ITA Airways

Also check the deals for one-way flights from San Diego to Rome in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Cheapest return flights from San Diego to Rome in December from 424€

Return flights