AirHint found the following cheapest one-way flights from San Diego (SAN) to Rome (FCO) in December 2025 (see full year).
One-Way flights
| 06 Dec | Alaska Airlines | ||
| 12 Dec | Alaska Airlines | ||
| 11 Dec | Hawaiian Airlines | ||
| 29 Dec | Frontier Airlines | ||
| 28 Dec | Lufthansa |
Also check the deals for return flights from San Diego to Rome in December.
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