AirHint found the following cheapest return flights from Rome (ROM) to Santiago (SCL) in November 2025 (see full year).

Return flights

12 Nov - 24 Nov	Iberia
21 Nov - 01 Dec	Iberia
06 Nov - 16 Nov	Delta
05 Nov - 16 Nov	Delta
10 Nov - 26 Nov	Delta
16 Nov - 27 Nov	Delta
07 Nov - 27 Nov	Delta
06 Nov - 07 Dec	Delta
16 Nov - 08 Dec	Iberia
13 Nov - 08 Dec	Delta
10 Nov - 08 Dec	Delta
29 Nov - 13 Dec	Iberia
16 Nov - 22 Nov	Delta
04 Nov - 18 Nov	Delta
17 Nov - 11 Dec	Iberia
05 Nov - 19 Nov	Delta
29 Nov - 10 Dec	Iberia
22 Nov - 07 Dec	Delta
19 Nov - 29 Nov	Iberia

Also check the deals for one-way flights from Rome to Santiago in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Santiago in November from 671€

Return flights