Cheapest return flights from Rome to Istanbul in April from 227€

AirHint found the following cheapest return flights from Rome (ROM) to Istanbul (IST) in April 2026 (see full year).

Return flights

27 Apr - 05 May Lufthansa
29 Apr - 06 May Lufthansa
01 Apr - 08 Apr Air France
02 Apr - 02 Apr Turkish Airlines direct
01 Apr - 06 Apr Turkish Airlines direct
01 Apr - 08 Apr Turkish Airlines direct
25 Apr - 02 May Turkish Airlines direct
03 Apr - 06 Apr Turkish Airlines direct
27 Apr - 01 May Turkish Airlines direct
02 Apr - 08 Apr Turkish Airlines direct
06 Apr - 12 Apr Turkish Airlines direct
01 Apr - 07 Apr Turkish Airlines direct
23 Apr - 29 Apr Turkish Airlines
24 Apr - 03 May Wizz Air Malta
24 Apr - 26 Apr Wizz Air Malta
27 Apr - 05 May Turkish Airlines direct

Also check the deals for one-way flights from Rome to Istanbul in April.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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