AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in September 2025 (see full year).

Return flights

10 Sep - 15 Sep	TAP
10 Sep - 27 Sep	TAP
13 Sep - 28 Sep	TAP
06 Sep - 28 Sep	TAP
16 Sep - 23 Sep	TAP
01 Sep - 08 Sep	TAP
06 Sep - 21 Sep	TAP
24 Sep - 29 Sep	TAP
17 Sep - 24 Oct	TAP
30 Sep - 28 Oct	TAP
28 Sep - 12 Oct	TAP
26 Sep - 12 Oct	TAP
23 Sep - 08 Oct	TAP
17 Sep - 24 Sep	TAP
30 Sep - 11 Oct	TAP
10 Sep - 28 Sep	KLM
03 Sep - 03 Oct	TAP
25 Sep - 06 Oct	TAP
20 Sep - 11 Oct	TAP
29 Sep - 14 Oct	TAP

Also check the deals for one-way flights from Rome to Sao Paulo in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in September from 547€

Return flights