AirHint found the following cheapest return flights from Rome (ROM) to Sao Paulo (GRU) in October 2025 (see full year).

Return flights

11 Oct - 25 Oct	TAP
07 Oct - 22 Oct	Delta
07 Oct - 27 Oct	Delta
09 Oct - 30 Oct	Delta
06 Oct - 29 Oct	Delta
07 Oct - 29 Oct	Delta
23 Oct - 29 Oct	Delta
06 Oct - 13 Oct	Delta
08 Oct - 15 Oct	Delta
23 Oct - 10 Nov	Delta
08 Oct - 27 Nov	Delta
09 Oct - 28 Nov	Delta
24 Oct - 26 Oct	TAP
29 Oct - 06 Nov	Air Europa
01 Oct - 06 Nov	Delta
15 Oct - 30 Nov	Delta
01 Oct - 13 Nov	Delta
01 Oct - 02 Nov	Delta
15 Oct - 24 Nov	Delta
31 Oct - 21 Nov	TAP

Also check the deals for one-way flights from Rome to Sao Paulo in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Rome to Sao Paulo in October from 676€

Return flights