AirHint found the following cheapest return flights from Raleigh-durham (RDU) to Rome (FCO) in October 2025 (see full year).

Return flights

01 Oct - 08 Oct	Frontier Airlines
01 Oct - 22 Oct	Frontier Airlines
13 Oct - 20 Oct	Frontier Airlines
06 Oct - 13 Nov	Air Canada
08 Oct - 20 Oct	Frontier Airlines
30 Oct - 06 Nov	United
20 Oct - 27 Oct	United
10 Oct - 17 Oct	Frontier Airlines
03 Oct - 12 Oct	Spirit Airlines
04 Oct - 14 Oct	Delta
25 Oct - 01 Nov	United
05 Oct - 20 Oct	Delta
05 Oct - 12 Oct	Icelandair

Also check the deals for one-way flights from Raleigh-durham to Rome in October.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rome

Cheap car rent in Rome

Cheapest return flights from Raleigh-durham to Rome in October from 370€

Return flights