AirHint found the following cheapest return flights from Panama City (PTY) to Santa Cruz (VVI) in August 2025 (see full year).

Return flights

07 Aug - 14 Aug	Avianca
08 Aug - 15 Aug	Avianca
10 Aug - 17 Aug	Avianca
11 Aug - 18 Aug	Avianca
13 Aug - 20 Aug	Avianca
08 Aug - 15 Aug	Copa	direct
10 Aug - 17 Aug	Copa	direct
11 Aug - 18 Aug	Copa	direct

Also check the deals for one-way flights from Panama City to Santa Cruz in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Santa Cruz in August from 478€

Return flights