AirHint found the following cheapest return flights from Panama City (PTY) to Mexico City (MEX) in May 2026 (see full year).

Return flights

08 May - 14 May	Avianca
15 May - 25 May	Avianca
15 May - 17 May	Avianca
15 May - 15 May	Avianca
24 May - 31 May	Avianca
15 May - 25 May	Copa	direct
08 May - 14 May	Copa	direct
15 May - 17 May	Copa	direct
24 May - 31 May	Copa	direct
31 May - 05 Jun	Avianca
15 May - 15 May	Copa	direct
31 May - 05 Jun	Copa	direct
18 May - 03 Jun	Avianca
27 May - 03 Jun	Avianca
16 May - 03 Jun	Avianca
12 May - 02 Jun	Avianca
18 May - 05 Jun	Avianca
18 May - 08 Jun	Avianca
18 May - 02 Jun	Avianca
27 May - 05 Jun	Avianca

Also check the deals for one-way flights from Panama City to Mexico City in May.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Mexico City in May from 276€

Return flights