AirHint found the following cheapest return flights from Panama City (PTY) to Mexico City (MEX) in November 2025 (see full year).

Return flights

18 Nov - 25 Nov	Copa	direct
14 Nov - 20 Nov	Copa	direct
30 Nov - 30 Dec	Avianca
03 Nov - 02 Dec	Copa	direct
25 Nov - 01 Dec	Copa	direct
21 Nov - 24 Nov	Avianca
16 Nov - 29 Nov	Copa	direct
10 Nov - 17 Nov	Copa	direct
16 Nov - 23 Nov	Copa	direct
23 Nov - 01 Dec	Copa	direct
17 Nov - 23 Nov	Avianca
13 Nov - 17 Nov	Avianca
03 Nov - 10 Nov	Avianca
21 Nov - 24 Nov	Copa	direct
28 Nov - 03 Dec	Copa	direct
28 Nov - 29 Dec	Copa	direct
28 Nov - 01 Dec	Copa	direct
30 Nov - 30 Dec	Copa	direct

Also check the deals for one-way flights from Panama City to Mexico City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Mexico City in November from 292€

Return flights