AirHint found the following cheapest return flights from Panama City (PTY) to Mexico City (MEX) in November 2025 (see full year).

Return flights

08 Nov - 10 Nov	Avianca
21 Nov - 24 Nov	Avianca
07 Nov - 10 Nov	Avianca
09 Nov - 12 Nov	Avianca
05 Nov - 12 Nov	Avianca
23 Nov - 01 Dec	Avianca
10 Nov - 17 Nov	Avianca
08 Nov - 14 Nov	Avianca
12 Nov - 19 Nov	Copa	direct
12 Nov - 16 Nov	Avianca
06 Nov - 10 Nov	Avianca
30 Nov - 04 Dec	Avianca
28 Nov - 03 Dec	Avianca
28 Nov - 03 Dec	Copa	direct
26 Nov - 16 Dec	Avianca
23 Nov - 01 Dec	Copa	direct
26 Nov - 16 Dec	Copa	direct
30 Nov - 04 Dec	Copa	direct

Also check the deals for one-way flights from Panama City to Mexico City in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Mexico City in November from 253€

Return flights