AirHint found the following cheapest return flights from Panama City (PTY) to Rio Negro (MDE) in September 2025 (see full year).

Return flights

09 Sep - 12 Sep	Wingo	direct
06 Sep - 09 Sep	Wingo	direct
09 Sep - 01 Oct	Wingo	direct
10 Sep - 01 Oct	Wingo	direct
28 Sep - 05 Oct	Wingo	direct
06 Sep - 13 Sep	Wingo	direct
22 Sep - 26 Sep	Wingo	direct
15 Sep - 19 Sep	Wingo	direct
12 Sep - 14 Sep	Wingo	direct
11 Sep - 15 Sep	Wingo	direct
12 Sep - 15 Sep	Wingo	direct
21 Sep - 27 Sep	Wingo	direct
20 Sep - 24 Sep	Wingo	direct
29 Sep - 06 Oct	Wingo	direct
12 Sep - 12 Oct	Copa	direct

Also check the deals for one-way flights from Panama City to Rio Negro in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Rio Negro

Cheap car rent in Rio Negro

Cheapest return flights from Panama City to Rio Negro in September from 126€

Return flights