AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in August 2025 (see full year).

Return flights

10 Aug - 25 Aug	Air France
11 Aug - 31 Aug	Air France
10 Aug - 30 Aug	Air France
11 Aug - 29 Aug	Air France
09 Aug - 24 Aug	Air France
03 Aug - 07 Sep	Air France
02 Aug - 07 Sep	Air France
02 Aug - 06 Sep	Air France
02 Aug - 19 Aug	Air France
04 Aug - 07 Sep	Air France
06 Aug - 22 Aug	Air France
08 Aug - 20 Aug	Air France
15 Aug - 24 Aug	Air France
09 Aug - 24 Aug	Iberia	direct
02 Aug - 06 Sep	Iberia	direct
01 Aug - 01 Sep	Air France
04 Aug - 07 Sep	Air Europa	direct
20 Aug - 07 Sep	Air France
20 Aug - 10 Sep	Air France
29 Aug - 14 Sep	Air France

Also check the deals for one-way flights from Panama City to Madrid in August.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Cheapest return flights from Panama City to Madrid in August from 610€

Return flights