Cheapest return flights from Panama City to Madrid in May from $657

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in May 2026 (see full year).

Return flights

14 May - 21 May Air France
07 May - 25 May Air France
12 May - 19 May Air France
03 May - 17 May Air France
05 May - 15 May Air France
04 May - 11 May Air France
07 May - 18 May Air France
03 May - 13 May Air France
11 May - 18 May Air France
07 May - 17 May Air France
17 May - 03 Jun Avianca
16 May - 03 Jun Avianca
26 May - 02 Jun Avianca
19 May - 03 Jun Avianca
18 May - 03 Jun Avianca
31 May - 14 Jun Avianca
26 May - 02 Jun Air Europa direct
30 May - 14 Jun Air Europa direct
17 May - 03 Jun Air Europa direct
18 May - 14 Jun Air Europa direct

Also check the deals for one-way flights from Panama City to Madrid in May.

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The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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