AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in November 2025 (see full year).

Return flights

04 Nov - 10 Nov	Avianca
01 Nov - 11 Nov	Avianca
14 Nov - 17 Nov	Avianca
10 Nov - 19 Nov	Iberia	direct
01 Nov - 15 Nov	Turkish Airlines
12 Nov - 15 Nov	Turkish Airlines
17 Nov - 06 Dec	Turkish Airlines
01 Nov - 07 Nov	Turkish Airlines
11 Nov - 27 Nov	Air Europa	direct
19 Nov - 01 Dec	Iberia	direct
01 Nov - 05 Nov	Turkish Airlines
04 Nov - 09 Nov	Turkish Airlines
17 Nov - 06 Dec	Iberia	direct
20 Nov - 10 Dec	Turkish Airlines
29 Nov - 15 Dec	Turkish Airlines
15 Nov - 15 Dec	Turkish Airlines
28 Nov - 03 Dec	Iberia
14 Nov - 08 Dec	Avianca
15 Nov - 15 Dec	Air Europa	direct
29 Nov - 15 Dec	Iberia	direct

Also check the deals for one-way flights from Panama City to Madrid in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Madrid in November from 611€

Return flights