Cheapest return flights from Panama City to Madrid in October from 609€

AirHint found the following cheapest return flights from Panama City (PTY) to Madrid (MAD) in October 2025 (see full year).

Return flights

30 Oct - 10 Nov Avianca
21 Oct - 31 Oct KLM
31 Oct - 17 Nov Avianca
12 Oct - 26 Oct Air France
24 Oct - 11 Nov Avianca
31 Oct - 11 Nov Avianca
01 Oct - 01 Nov Air France
13 Oct - 29 Oct Iberia direct
13 Oct - 25 Oct KLM
22 Oct - 07 Nov Turkish Airlines
09 Oct - 23 Oct Iberia direct
17 Oct - 24 Oct Air Europa direct
16 Oct - 23 Oct Iberia direct
31 Oct - 22 Nov Avianca
23 Oct - 30 Oct Turkish Airlines
01 Oct - 15 Oct Air France
12 Oct - 22 Oct Air Europa direct
31 Oct - 08 Nov Avianca
31 Oct - 09 Nov Avianca
20 Oct - 03 Nov Avianca

Also check the deals for one-way flights from Panama City to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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