Cheapest one-way flights from Panama City to Madrid in October from 343€

AirHint found the following cheapest one-way flights from Panama City (PTY) to Madrid (MAD) in October 2025 (see full year).

One-Way flights

01 Oct Avianca
10 Oct Avianca
06 Oct Turkish Airlines
29 Oct KLM
25 Oct Air France
28 Oct Turkish Airlines
25 Oct Air Europa direct
01 Oct Air Europa direct
06 Oct Air Europa direct
28 Oct Air Europa direct

Also check the deals for return flights from Panama City to Madrid in October.

Skyscanner

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Madrid

Cheap car rent in Madrid

Feel free to contact us with any feedback or request another flight research.