AirHint found the following cheapest return flights from Panama City (PTY) to Istanbul (IST) in November 2025 (see full year).

Return flights

30 Nov - 08 Dec	Air Europa
04 Nov - 07 Nov	Air Europa
05 Nov - 08 Nov	Turkish Airlines
01 Nov - 22 Nov	Air France
01 Nov - 05 Nov	Air Europa
01 Nov - 12 Nov	Turkish Airlines	direct
02 Nov - 06 Nov	Air Europa
01 Nov - 22 Nov	Turkish Airlines	direct
01 Nov - 29 Nov	Turkish Airlines	direct
30 Nov - 08 Dec	Turkish Airlines	direct
15 Nov - 29 Nov	Air France
15 Nov - 29 Nov	Turkish Airlines	direct

Also check the deals for one-way flights from Panama City to Istanbul in November.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Istanbul in November from 941€

Return flights