AirHint found the following cheapest return flights from Panama City (PTY) to Guayaquil (GYE) in February 2026 (see full year).

Return flights

04 Feb - 22 Feb	Avianca
01 Feb - 15 Feb	Copa	direct
01 Feb - 15 Feb	Avianca
14 Feb - 28 Feb	Copa	direct
14 Feb - 28 Feb	Avianca
13 Feb - 22 Feb	Copa	direct
07 Feb - 14 Feb	Copa	direct
04 Feb - 22 Feb	Copa	direct

Also check the deals for one-way flights from Panama City to Guayaquil in February.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Guayaquil in February from 221€

Return flights