Cheapest return flights from Panama City to Guayaquil in December from 294€

AirHint found the following cheapest return flights from Panama City (PTY) to Guayaquil (GYE) in December 2025 (see full year).

Return flights

11 Dec - 14 Dec Avianca
07 Dec - 17 Dec Avianca
12 Dec - 14 Dec Avianca
02 Dec - 05 Dec Avianca
27 Dec - 18 Jan Avianca
13 Dec - 25 Jan Avianca
18 Dec - 24 Dec Avianca
19 Dec - 07 Jan Copa direct
19 Dec - 21 Dec Copa direct
18 Dec - 24 Dec Copa direct
12 Dec - 14 Dec Copa direct
13 Dec - 25 Jan Copa direct
07 Dec - 17 Dec Copa direct
02 Dec - 05 Dec Copa direct

Also check the deals for one-way flights from Panama City to Guayaquil in December.

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