AirHint found the following cheapest return flights from Panama City (PTY) to Frankfurt (FRA) in December 2025 (see full year).

Return flights

11 Dec - 08 Jan	Condor	direct
22 Dec - 05 Jan	Condor	direct
08 Dec - 15 Dec	Condor	direct
06 Dec - 13 Dec	Air France
12 Dec - 09 Jan	Air France
11 Dec - 23 Dec	Air France
15 Dec - 25 Dec	Air France
15 Dec - 25 Dec	Condor	direct
18 Dec - 29 Dec	KLM
18 Dec - 28 Dec	KLM
09 Dec - 16 Dec	Air France
18 Dec - 29 Dec	Condor	direct
20 Dec - 03 Jan	Turkish Airlines
11 Dec - 18 Dec	Condor	direct

Also check the deals for one-way flights from Panama City to Frankfurt in December.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

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Cheapest return flights from Panama City to Frankfurt in December from 820€

Return flights