AirHint found the following cheapest return flights from Prague (PRG) to Panama City (PTY) in December 2025 (see full year).
Return flights
| 04 Dec - 15 Dec | Condor | ||
| 04 Dec - 18 Dec | Condor | ||
| 14 Dec - 22 Dec | Ryanair | ||
| 17 Dec - 30 Dec | Air Serbia | ||
| 26 Dec - 01 Jan | Ryanair | ||
| 26 Dec - 03 Jan | Ryanair | ||
| 26 Dec - 02 Jan | easyJet |
Also check the deals for one-way flights from Prague to Panama City in December.
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