AirHint found the following cheapest return flights from Prague (PRG) to Mexico City (MEX) in September 2025 (see full year).

Return flights

17 Sep - 25 Sep	Condor
21 Sep - 12 Oct	Condor
21 Sep - 25 Sep	Condor
19 Sep - 21 Sep	Ryanair
20 Sep - 27 Sep	Wizz Air UK
25 Sep - 04 Oct	Ryanair
18 Sep - 21 Sep	easyJet
28 Sep - 05 Oct	TAP
08 Sep - 15 Sep	easyJet
10 Sep - 13 Sep	Ryanair
10 Sep - 18 Sep	Ryanair
11 Sep - 15 Sep	Ryanair
07 Sep - 11 Sep	Turkish Airlines

Also check the deals for one-way flights from Prague to Mexico City in September.

The deals are updated regularly. The prices may go up as tickets are purchased by other travellers. Only the cheapest flights are offered. Select a price to book and secure these cheap prices.

Book a cheap hotel in Mexico City

Cheap car rent in Mexico City

Cheapest return flights from Prague to Mexico City in September from 661€

Return flights